Septerna Inc. – Material Contracts Watch

from 10-Q 4 pages Septerna, Inc. Amended and Restated Non-Employee Director Compensation Policy

from 10-K 8 pages January 6, 2026 Mark A. Wilson, Jd 1613 Ray Drive Burlingame, Ca 94010 Re: Offer of Employment by Septerna, Inc. 3. Compensation and Related Matters

from 10-Q 3 pages Septerna, Inc. Amended and Restated Non-Employee Director Compensation Policy

from 10-Q 128 pages Collaboration and License Agreement Between Novo Nordisk a/S and Septerna, Inc

from 8-K 7 pages Re: Offer of Employment by Septerna, Inc. Dear Gil: On Behalf of Septerna, Inc. (The “Company”), I Am Pleased to Confirm Our Offer to Employ You as Our Chief Financial Officer the Initial Terms and Conditions of Your Employment, Should You Accept This Offer, Are Set Forth Below in This Letter Agreement (The “Agreement”)

from S-1/A 13 pages Septerna, Inc. Executive Severance Plan

from S-1/A 7 pages Septerna, Inc. Compensation Recovery Policy Adopted as of October 1, 2024, Subject to Effectiveness of the Company’s Registration Statement on Form S-1 for Its Initial Public Offering

from S-1/A 3 pages Septerna, Inc. Senior Executive Cash Incentive Bonus Plan

from S-1/A 3 pages Septerna, Inc. Non-Employee Director Compensation Policy

from S-1/A 10 pages Re: Offer of Employment by Septerna, Inc. Dear Daniel: On Behalf of Septerna, Inc. (The “Company”), I Am Pleased to Confirm Our Offer to Employ You as Senior Vice President, Drug Discovery. the Initial Terms and Conditions of Your Employment, Should You Accept This Offer, Are Set Forth Below in This Letter Agreement (The “Agreement”)

from S-1/A 10 pages February 17, 2021 Uwe Klein Re: Offer of Employment by Gpcr Newco Inc. Dear Uwe, on Behalf of Gpcr Newco Inc. (The “Company”), I Am Pleased to Confirm Our Offer to Employ You as Senior Vice President, Biological Sciences. the Initial Terms and Conditions of Your Employment, Should You Accept This Offer, Are Set Forth Below in This Letter Agreement (The “Agreement”)

from S-1/A 10 pages December 22, 2022 Samira Shaikhly Re: Offer of Employment by Septerna, Inc. Dear Samira: On Behalf of Septema, Inc. (The “Company”), I Am Pleased to Confirm Our Offer to Employ You as Chief People Officer. the Initial Terms and Conditions of Your Employment, Should You Accept This Offer, Are Set Forth Below in This Letter Agreement (The “Agreement”)

from S-1/A 10 pages Re: Offer of Employment by Septerna, Inc. Dear Jae: On Behalf of Septerna, Inc. (The “Company”), I Am Pleased to Confirm Our Offer to Employ You as Our Chief Medical Officer. the Initial Terms and Conditions of Your Employment, Should You Accept This Offer, Are Set Forth Below in This Letter Agreement (The “Agreement”)

from S-1/A 9 pages Re: Offer of Employment by Septerna, Inc. Dear Liz: On Behalf of Septerna, Inc. (The “‘Company”), I Am Pleased to Confirm Our Offer to Employ You as Chief Operating Officer. the Initial Terms and Conditions of Your Employment, Should You Accept This Offer, Are Set Forth Below in This Letter Agreement (The “Agreement”)

from S-1/A 5 pages 1. Position. as Vice President, Finance and Business Operations You Will Report to Jeff Finer, President & Chief Executive Officer, or Another Duly Authorized Manager or Executive. This Is a Full-Time, Exempt Position. It Is Understood and Agreed That, While You Render Services to the Company, You Will Not Engage in Any Other Employment, Consulting, or Other Business Activities (Whether Full-Time or Part-Time), Except as Expressly Authorized in Writing by the Company’s Chief Executive Officer (The “CEO”). Notwithstanding the Foregoing, You May Engage in Religious, Charitable, and Other Community Activities So Long as Such Activities Do Not Interfere or Conflict With Your Obligations to the Company. 2. Start Date. Your Employment With the Company Will Begin on February 28, 2022, Unless Another Date Is Agreed to by You and the Company. the Actual First Day of Your Employment With the Company Shall Be Referred to Herein as the “Start Date.” 3. Compensation and Related Matters

from S-1/A 9 pages Re: Offer of Employment by Septerna, Inc. Dear Jeff: On Behalf of Septerna, Inc. (The “Company”), I Am Pleased to Confirm Our Offer to Employ You as Chief Executive Officer (“CEO”). the Initial Terms and Conditions of Your Employment, Should You Accept This Offer, Are Set Forth Below in This Letter Agreement (The “Agreement”)

from S-1/A 17 pages Septerna, Inc. Form of Employee Director / Officer Indemnification Agreement

from S-1/A 17 pages Septerna, Inc. Form of Non-Employee Director Indemnification Agreement

from S-1/A 10 pages Septerna, Inc. 2024 Employee Stock Purchase Plan

from S-1/A 52 pages Septerna, Inc. 2024 Stock Option and Incentive Plan