Tourmaline Bio Inc. – Material Contracts Watch

from 10-Q ~5 pages •employment Status: Your Status Will Change From Full-Time to Part-Time, Effective April 1, 2025. as a Part-Time Employee, You Will Be Working an Average of 28 Hours Per Week, Anticipated to Be Worked Mondays – Thursdays With Flexibility That Is Mutually Agreeable Between You and Your Manager, the Chief Executive Officer, Based on Personal and Business Needs. •job Title and Duties: Your Job Title Will Remain Chief Technology Officer, and Your Primary Duties and Responsibilities Will Remain the Same. •base Compensation: Your Base Compensation Will Be $296,800. •annual Discretionary Bonus Target: 40% (No Change)1 •benefits: There Will Be No Change to Your Benefits Eligibility. •equity: There Will Be No Change to the Vesting Schedule for Equity Granted to Date. Please Sign Below to Acknowledge Your Understanding and Acceptance of the Terms Outlined in This Letter. Employee Acknowledgement: I, Susan Dana Jones, Acknowledge and Agree to the Terms of the New Part-Time Employment Arrangement Outlined Above, Effective April 1, 2025. /S/ Susan Dana Jones March 24, 2025 Signature Date Tourmaline Representative: Brad Middlekauff Chief Business Officer Name Title /S/ Brad Middlekauff May 15, 2025 Signature Date

from 10-Q 2 pages Tourmaline Bio, Inc. Non-Employee Director Compensation Policy Originally Adopted: October 23, 2023 Last Amended and Restated: April 2, 2025

from 10-Q 6 pages Tourmaline Bio, Inc

from 10-Q 3 pages Tourmaline Bio, Inc. Non-Employee Director Compensation Policy Originally Adopted: October 23, 2023 Amended and Restated: April 3, 2024

from 10-Q 1 page November 9, 2023 Ryan Robinson 28 Winship Drive Stoneham, Ma 02180 Re: Interim CFO – Additional Compensation Dear Ryan: Sincerely, /S/ Sandeep Kulkarni Name: Sandeep Kulkarni Title: Chief Executive Officer Accepted: /S/ Ryan Robinson 11/10/2023 Ryan Robinson Date

from 8-K 3 pages Tourmaline Bio, Inc. Non-Employee Director Compensation Policy Adopted: October 23, 2023

from 8-K 20 pages Tourmaline Bio, Inc. Executive Severance and Change in Control Plan Effective Date: October 23, 2023

from 8-K 13 pages Tourmaline Bio, Inc. 2023 Employee Stock Purchase Plan Adopted by the Board of Directors: June 22, 2023 Approved by the Stockholders: October 17, 2023

from 8-K 7 pages Tourmaline Bio, Inc. Rsu Award Grant Notice

from 8-K 8 pages Tourmaline Bio, Inc. Stock Option Grant Notice

from 8-K 34 pages Tourmaline Bio, Inc. 2023 Equity Incentive Plan Adopted by the Board of Directors: June 22, 2023 Approved by the Stockholders: October 17, 2023

from 8-K 2 pages Offer Letter

from 8-K 6 pages Tourmaline Bio, Inc

from 8-K 6 pages Tourmaline Bio, Inc

from 8-K 5 pages Tourmaline Bio, Inc

from S-4/A 1 page August 25, 2023 Scott Requadt Re: Amendment to Strategic Advisor Agreement Dear Scott

from S-4 14 pages Indemnification Agreement

from S-4 6 pages Strategic Advisor Agreement

from S-4 22 pages Licence Agreement Between Lonza Sales AG and Tourmaline Bio, LLC

from S-4 45 pages License Agreement