| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Chevallard Daniel R. Chief Financial Officer | A | Stock Option (right to buy) | |||||
| RA Capital Healthcare Fund LP | S | Common Stock | |||||
| Ra Capital Management, L.P. | S | Common Stock | |||||
| Kolchinsky Peter | S | Common Stock | |||||
| Shah Rajeev M. | S | Common Stock |