| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Edelman Joseph | P | Ordinary Shares | |||||
| Perceptive Advisors LLC | P | Ordinary Shares | |||||
| Perceptive Life Sciences Master Fund Ltd | P | Ordinary Shares | |||||
| Pepin James Nelson Gen Counsel and Corp Secretary | A | Restricted Stock Units | |||||
| Pepin James Nelson Gen Counsel and Corp Secretary | A | Stock Option (Right to Buy) |