Design Therapeutics Inc. – Material Contracts Watch

from 10-Q 6 pages Second Amendment to Lease

from 10-Q 3 pages Each Member of the Board of Directors (The “Board”) Who Is Not Also Serving as an Employee of or Consultant to Design Therapeutics, Inc. (The “Company”) or Any of Its Subsidiaries (Each Such Member, an “Eligible Director”) Will Receive the Compensation Described in This Non-Employee Director Compensation Policy for His or Her Board Service. an Eligible Director May Decline All or Any Portion of His or Her Compensation by Giving Notice to the Company Prior to the Date Cash May Be Paid or Equity Awards Are to Be Granted, as the Case May Be. Annual Cash Compensation

from 10-K 5 pages 298588649 V2 April 9, 2025 Chris M. Storgard, MD Re: Employment Terms

from 10-K 44 pages Design Therapeutics, Inc. 2021 Equity Incentive Plan Adopted by the Board of Directors: March 18, 2021 Approved by the Stockholders: March 19, 2021 Amended by the Compensation Committee of the Board of Directors: December 2, 2024

from 10-K 12 pages Design Therapeutics, Inc. Consulting Agreement

from 10-K 3 pages Design Therapeutics, Inc. Third Amendment to Consulting Agreement [Signature Page Follows] 1 of 2

from 10-K 3 pages Each Member of the Board of Directors (The “Board”) Who Is Not Also Serving as an Employee of or Consultant to Design Therapeutics, Inc. (The “Company”) or Any of Its Subsidiaries (Each Such Member, an “Eligible Director”) Will Receive the Compensation Described in This Non-Employee Director Compensation Policy for His or Her Board Service Upon and Following the Date of the Underwriting Agreement Between the Company and the Underwriters Managing the Initial Public Offering of the Company’s Common Stock (The “Common Stock”), Pursuant to Which the Common Stock Is Priced in Such Initial Public Offering (The “Effective Date”). an Eligible Director May Decline All or Any Portion of His or Her Compensation by Giving Notice to the Company Prior to the Date Cash May Be Paid or Equity Awards Are to Be Granted, as the Case May Be. This Policy Is Effective as of the Effective Date, as Amended by the Board on December 12, 2023, Effective as of January 1, 2024, and as May Be Further Amended at Any Time in the Sole Discretion of the Board or the Compensation Committee of the Board. Annual Cash Compensation

from 10-Q 12 pages August 25, 2023 João Siffert, M.D. Re: Separation Agreement Dear João: This Letter Sets Forth the Substance of the Separation Agreement (The “Agreement”) That Design Therapeutics, Inc. (The “Company”) Is Offering to You to Aid in Your Employment Transition. 1

from 8-K 11 pages First Amendment to Lease

from 10-K 49 pages Design Therapeutics, Inc. 2021 Equity Incentive Plan Adopted by the Board of Directors: March 18, 2021 Approved by the Stockholders: March 19, 2021

from S-1/A 14 pages Design Therapeutics, Inc. Consulting Agreement

from S-1/A 5 pages Design Therapeutics Consulting Agreement Effective Date: March 1, 2020

from S-1/A 2 pages Design Therapeutics, Inc. Non-Employee Director Compensation Policy

from S-1/A 11 pages Design Therapeutics, Inc. 2021 Employee Stock Purchase Plan Adopted by the Board of Directors: March 18, 2021 Approved by the Stockholders: March 19, 2021

from S-1/A 60 pages Design Therapeutics, Inc. 2021 Equity Incentive Plan Adopted by the Board of Directors: March 18, 2021 Approved by the Stockholders: March 19, 2021

from S-1 30 pages Basic Lease Provisions and Definitions

from S-1 5 pages Design Therapeutics Consulting Agreement Effective Date: March 1, 2020

from S-1 29 pages Human Therapeutics Exclusive License Agreement

from S-1 2 pages May 21, 2019 Sean Jeffries Re: Employment Terms Dear Sean: Design Therapeutics, Inc. (The “Company”) Is Pleased to Offer You the Position of Principal Scientist/Chief Business Officer on the Terms Set Forth Below. This Offer Is Subject to the Following Conditions: • as Required by Law, the Company Receipt of Satisfactory Proof of Your Right to Work in the United States

from S-1 10 pages September 21, 2020 Joao Siffert Re: Offer of Employment Dear Joao: Design Therapeutics, Inc. (The “Company”) Is Pleased to Offer You At-Will Employment in the Position of Chief Executive Officer (“CEO”) on the Terms and Conditions Set Forth in This Letter Agreement (The “Agreement”)