| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Matsuda Masaru EVP, Chief Legal Officer | M | Common Stock | |||||
| Matsuda Masaru EVP, Chief Legal Officer | M | Stock Option (right to buy) | |||||
| Matsuda Masaru EVP, Chief Legal Officer | S | Common Stock | |||||
| Burnett Patrick EVP, Chief Medical Officer | S | Common Stock | |||||
| Watanabe Todd See Remarks | S | Common Stock |