Kiniksa Pharmaceuticals International plc – Indentures Watch

from 8-K12B 7 pages Description of Share Capital

from 8-K12B 2 pages Indenture or similar

from S-3 49 pages Kiniksa Pharmaceuticals International, PLC Indenture Dated as of , 20__ [ ] Trustee

from S-3 51 pages Kiniksa Pharmaceuticals, Ltd. Indenture Dated as of , 20 [ ] Trustee

from 10-K 6 pages Description of Share Capital

from S-3 46 pages Kiniksa Pharmaceuticals, Ltd. Indenture Dated as of [ ], 20[ ] [ ] Trustee

from S-1/A 2 pages Class a Common Shares Class a Common Shares Kpl Kiniksa Pharmaceuticals, Ltd. Incorporated Under the Laws of Bermuda Cusip See Reverse for Certain Definitions This Certifies That Is the Record Holder of Fully Paid and Non-Assessable Class a Common Shares, US $.000273235 Par Value Per Share, of Kiniksa Pharmaceuticals, Ltd. Held Subject to the Memorandum of Association and Bye-Laws of the Company and Transferable in Accordance Therewith. This Certificate Is Not Valid Until Countersigned by the Transfer Agent and Registered by the Registrar. Witness the Facsimile Seal of the Company and the Facsimile Signature of Its Duly Authorized Officer. Dated: Bermuda 20 1 8 Chairman and Chief Executive Officer Countersigned and Registered: American Stock Transfer & Trust Company, LLC (Brooklyn, Ny) Transfer Agent and Registrar By: Authorized Signature

from S-1 47 pages Kiniksa Pharmaceuticals, Ltd. Second Amended and Restated Investors’ Rights Agreement

from DRS 47 pages Kiniksa Pharmaceuticals, Ltd. Second Amended and Restated Investors’ Rights Agreement