| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Russell Alan J Chief Scientific Officer | M | Common Stock | |||||
| Russell Alan J Chief Scientific Officer | M | Stock Option (Right to Buy) | |||||
| Russell Alan J Chief Scientific Officer | S | Common Stock | |||||
| Fox Jonathan C | A | Common Stock | |||||
| Martin Christopher Nathan | A | Stock Options (Right to buy) |