| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Fairmount Healthcare Fund II L.P. | P | Common Stock | |||||
| Fairmount Funds Management LLC | P | Common Stock | |||||
| Fairmount Healthcare Fund II GP LLC | P | Common Stock | |||||
| Harmon Seth Chief Financial Officer | F | Common Stock | |||||
| Beetham Thomas W. Chief Operating Officer | F | Common Stock |