| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Deerfield Management Company, L.P. | D | Warrant to Purchase Common Stock | |||||
| Flynn James E | D | Warrant to Purchase Common Stock | |||||
| Mukai Takeo CFO | F | Form 4 | |||||
| Sohn Tom SVP, Gen. Counsel & Secretary | F | Form 4 | |||||
| Mukai Takeo CFO | F | Form 4 |