| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Eshelman Fredric N | D | Common Stock | |||||
| Eshelman Fredric N | D | Stock Options (to buy) | |||||
| McIntyre Gail Frances Senior Vice President-Research | D | Common Stock | |||||
| McIntyre Gail Frances Senior Vice President-Research | D | Stock Options (to buy) | |||||
| Covington Paul S Senior VP-Clinical Operations | D | Common Stock |