| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Opaleye Management Inc. | P | Common Stock, par value $0.0001 per share | |||||
| Neugeboren Edward | A | Stock Option (Right to Buy) | |||||
| Davis a Brian | A | Stock Option (Right to Buy) | |||||
| Kavuru Vimal | A | Stock Option (Right to Buy) | |||||
| Kottayil George | A | Stock Option (Right to Buy) |