| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Hamilton Thomas Edward | P | Common Stock | |||||
| Deerfield Management Company, L.P. | A | Stock Option (Right to Buy) | |||||
| Flynn James E | A | Stock Option (Right to Buy) | |||||
| Leff Jonathan S | A | Stock Option (Right to Buy) | |||||
| Sherman Jeffrey W | A | Stock Option (Right to Buy) |