Cadence Pharmaceuticals Inc – Indentures Watch

from 8-K 11 pages Warrant to Purchase Stock

from 8-K 10 pages Warrant to Purchase Stock

from 8-K 11 pages Warrant to Purchase Stock

from S-3 56 pages Form of Indenture to Be Entered Into Between the Company and a Trustee to Be Named Cadence Pharmaceuticals, Inc. Indenture Dated as of , 20__ [Name of Trustee] Trustee

from 8-K 13 pages Warrant to Purchase Stock

from 8-K 13 pages Warrant to Purchase Stock

from 8-K 13 pages Warrant to Purchase Stock

from 8-K 10 pages Cadence Pharmaceuticals, Inc. Registration Rights Waiver and Amendment November 29, 2007

from 10-Q 3 pages Stock Certificate Cusip 12738t 10 0

from S-1/A 3 pages [Face of Certificate] Number Cp Common Stock [Logo] Cadence Pharmaceuticals, Inc. Incorporated Under the Laws of the State of Delaware Shares See Reverse for Statements Relating to Rights, Preferences, Privileges and Restrictions, if Any This Certifies That Is the Record Holder of Fully Paid and Nonassessable Shares of the Common Stock, $.0001 Par Value Per Share, of Cadence Pharmaceuticals, Inc. Transferable on the Books of the Corporation by the Holder Hereof in Person or by Duly Authorized Attorney Upon Surrender of This Certificate Properly Endorsed. This Certificate Is Not Valid Unless Countersigned and Registered by the Transfer Agent and Registrar. Witness the Facsimile Seal of the Corporation and the Facsimile Signatures of Its Duly Authorized Officers. Dated: /Sig/ Senior Vice President & CFO [Seal] /Sig/ President & CEO Countersigned and Registered: American Stock Transfer & Trust Company Transfer Agent and Registrar by Authorized Signature

from S-1 14 pages Warrant to Purchase Stock

from S-1 14 pages Warrant to Purchase Stock

from S-1 56 pages Cadence Pharmaceuticals, Inc. Amended and Restated Investor Rights Agreement February 21, 2006 Cadence Pharmaceuticals, Inc. Amended and Restated Investor Rights Agreement Recitals