| Date | Issuer | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Theravance Biopharma Inc. | A | Ordinary Shares | |||||
| Theravance Biopharma Inc. | A | Share Option (Right to Buy) | |||||
| Karyopharm Therapeutics Inc. | A | Common Stock | |||||
| Mereo BioPharma Group plc | A | Share Options (Right to buy) | |||||
| Karyopharm Therapeutics Inc. | A | Nonstatutory Stock Option (right to buy) |