| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Nagao Hideki | A | Stock Option (Right to Buy) | |||||
| Lemerond Nicole | A | Stock Option (Right to Buy) | |||||
| Beaver Carolyn | A | Stock Option (Right to Buy) | |||||
| Matsuda Kazuko Chief Medical Officer | A | Employee Stock Option (Right to Buy) | |||||
| Iwaki Yuichi President and CEO | A | Employee Stock Option (Right to Buy) |