| Date | Owner | Type | Security | Price | Units | Value | |
|---|---|---|---|---|---|---|---|
| Cioffi Christiana Marie Chief Strategy Officer | A | Common shares | |||||
| Sayad Pierre Sargis Chief Medical Officer | A | Common Shares | |||||
| Evans Terry L Chief Commercial Officer | A | Common Shares | |||||
| Hackman Jeffrey S. Chief Executive Officer | A | Common Shares | |||||
| Andrade Robert CHIEF FINANCIAL OFFICER | A | Common shares |